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Are you in genomics and building models? Stop using ROC - use PR

tldr Area Under the Curve (AUC) of Receiver Operating Characteristic (ROC) is a terrible metric for a genomics problem. Do not use it. This metric also goes by AUC or AUROC. Use Precision Recall AUC. Inspiration for this post I am working on a machine learning problem in genomics I was getting really confused why AUROC was so worthless scienceTwitter featuring Anshul Kundaje I want to save you (some time) What’s a ROC?